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ELK Biotechnology Nrf2 (Acetyl Lys599) rabbit pAb
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Nrf2 단백질의 Lys599 아세틸화 부위를 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 시료에 반응하며 세포 내 산화 스트레스 반응 연구에 적합. -20°C에서 1년 보관.
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- pk
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ELK Biotechnology ES1138-100UL Nrf2 (Acetyl Lys599) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1138-50UL Nrf2 (Acetyl Lys599) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Nrf2 (Acetyl Lys599) rabbit pAb
제품명
Nrf2 (Acetyl Lys599) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 IHC-p: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized acetyl-peptide derived from the C-terminal region of human Nrf2 around the acetylation site of K599 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 75-100 kDa |
| Gene ID (Human) | 4780 |
| Human Swiss-Prot No. | Q16236 |
| Cellular Localization | Cytoplasm, cytosol, nucleus. Under unstressed conditions, cytosolic and ubiquitinated by the BCR(KEAP1) E3 ubiquitin ligase complex. Translocates into the nucleus upon induction by electrophilic agents that inactivate the complex. |
| Species Reactivity | Human; Mouse; Rat |
배경 (Background)
This gene encodes a transcription factor belonging to the basic leucine zipper (bZIP) protein family. It regulates genes containing antioxidant response elements (ARE) in their promoters, many of which are involved in cellular defense against injury and inflammation, including free radical response. Multiple transcript variants encoding different isoforms have been identified.
[Provided by RefSeq, Sep 2015]
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