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ELK Biotechnology Nrf2 (Acetyl Lys599) rabbit pAb
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ELK Biotechnology Nrf2 (Acetyl Lys599) rabbit pAb

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Nrf2 단백질의 Lys599 아세틸화 부위를 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 시료에 반응하며 세포 내 산화 스트레스 반응 연구에 적합. -20°C에서 1년 보관.

판매단위
pk
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ELK Biotechnology ES1138-100UL Nrf2 (Acetyl Lys599) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1138-50UL Nrf2 (Acetyl Lys599) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Nrf2 (Acetyl Lys599) rabbit pAb

제품명

Nrf2 (Acetyl Lys599) rabbit pAb

제품 정보

항목 내용
Alternative Names NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
IHC-p: 1/100 - 1/300
ELISA: 1/10000
Not yet tested in other applications
Immunogen Synthesized acetyl-peptide derived from the C-terminal region of human Nrf2 around the acetylation site of K599
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 75-100 kDa
Gene ID (Human) 4780
Human Swiss-Prot No. Q16236
Cellular Localization Cytoplasm, cytosol, nucleus. Under unstressed conditions, cytosolic and ubiquitinated by the BCR(KEAP1) E3 ubiquitin ligase complex. Translocates into the nucleus upon induction by electrophilic agents that inactivate the complex.
Species Reactivity Human; Mouse; Rat

배경 (Background)

This gene encodes a transcription factor belonging to the basic leucine zipper (bZIP) protein family. It regulates genes containing antioxidant response elements (ARE) in their promoters, many of which are involved in cellular defense against injury and inflammation, including free radical response. Multiple transcript variants encoding different isoforms have been identified.
[Provided by RefSeq, Sep 2015]

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