ELK Biotechnology Tubulin α (Acetyl Lys112) rabbit pAb
Tubulin α (Acetyl Lys112) rabbit pAb는 인간, 마우스, 랫트에서 반응하는 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 미세소관 단백질 α-튜불린의 아세틸화 K112 부위를 인식하며, 세포질 및 세포골격에 위치한 단백질 연구에 유용합니다.
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Tubulin α (Acetyl Lys112) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Tubulin α (Acetyl Lys112) rabbit pAb |
| Alternative Names | TUBA1A; TUBA3; Tubulin alpha-1A chain; Alpha-tubulin 3; Tubulin B-alpha-1; Tubulin alpha-3 chain; TUBA1B; Tubulin alpha-1B chain; Alpha-tubulin ubiquitous; Tubulin K-alpha-1; Tubulin alpha-ubiquitous chain; TUBA1C; TUBA6; Tubulin alpha-1C chain; Alpha-tubulin 6; Tubulin alpha-6 chain |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000; ELISA: 1/20000; Not yet tested in other applications |
| Immunogen | Synthesized acetyl-peptide derived from human Tubulin α around the acetylation site of K112 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| GeneID (Human) | 7846 / 10376 / 84790 |
| Human Swiss-Prot No | Q71U36 / P68363 / Q9BQE3 |
| Cellular Localization | Cytoplasm, cytoskeleton |
| Species Reactivity | Human; Mouse; Rat |
Background
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which includes six distinct families. Genes from the alpha, beta, and gamma tubulin families are found in all eukaryotes. Alpha and beta tubulins are the major components of microtubules, while gamma tubulin plays a critical role in microtubule nucleation. Multiple alpha and beta tubulin genes are highly conserved among species. This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 genes. Northern blot studies show predominant expression in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes clustered on chromosome 12q.
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