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ELK Biotechnology Ku-70 (Acetyl Lys331) rabbit pAb
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ELK Biotechnology Ku-70 (Acetyl Lys331) rabbit pAb

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Ku-70 (Acetyl Lys331) rabbit pAb은 인간 Ku70 단백질의 Lys331 아세틸화 부위에 특이적으로 반응하는 폴리클로날 항체입니다. WB와 IHC에 적합하며, 핵 내 DNA 수선 관련 Ku 복합체 연구에 활용됩니다. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관 가능합니다.

판매단위
pk
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ELK Biotechnology ES1118-100UL Ku-70 (Acetyl Lys331) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1118-50UL Ku-70 (Acetyl Lys331) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Ku-70 (Acetyl Lys331) rabbit pAb

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Ku-70 (Acetyl Lys331) rabbit pAb

공급업체

ELK Biotechnology

제품 정보

항목 내용
Alternative Names XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; CTC box-binding factor 75 kDa subunit; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA
Applications WB; IHC
Recommended Dilutions WB: 1:500–2000; IHC-p: 1:50–300
Immunogen Synthesized Acetyl-peptide derived from human Ku70 around Lys331 (AA range: 291–340)
Host Rabbit
Storage -20°C, 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 70 kDa
Gene ID (Human) 2547
Human Swiss-Prot No. P12956
Cellular Localization Nucleus, Chromosome
Species Reactivity Human; Mouse; Rat

Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. This complex functions as a single-stranded DNA-dependent ATP-dependent helicase and may be involved in the repair of nonhomologous DNA ends, including double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been detected in some patients with systemic lupus erythematosus.
(provided by RefSeq, Jul 2008)

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