
ELK Biotechnology p73 (Acetyl Lys327) rabbit pAb
p73 단백질의 Lys327 아세틸화 부위를 인식하는 토끼 폴리클로날 항체. WB 및 ELISA에 적합하며 인간, 마우스, 랫에서 반응. 세포 스트레스 반응 연구 및 종양 억제 유전자 기능 분석에 활용 가능.
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제품명
p73 (Acetyl Lys327) rabbit pAb
제품 개요
이 항체는 인간 p73 단백질의 Lys327 아세틸화 부위를 인식하도록 제작된 토끼 폴리클로날 항체입니다. p53 패밀리 단백질로서 세포 스트레스 및 종양 억제 관련 연구에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | p73 (Acetyl Lys327) rabbit pAb |
| Alternative Names | TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized Acetyl-peptide derived from human p73 around the Acetylation site of Lys327 (AA range: 291–340) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 70 kD |
| Gene ID (Human) | 7161 |
| Human Swiss-Prot No. | O15350 |
| Cellular Localization | Nucleus, Cytoplasm (Accumulates in the nucleus in response to DNA damage) |
| Species Reactivity | Human; Mouse; Rat |
Background
Tumor protein p73 (TP73) is a member of the p53 family of transcription factors involved in cellular responses to stress and development. It is located on chromosome 1p36, a region frequently deleted in neuroblastoma and other tumors, suggesting the presence of multiple tumor suppressor genes. The gene is monoallelically expressed, likely from the maternal allele, making it a candidate gene for neuroblastoma. Multiple transcript variants exist due to alternative splicing and promoter usage, though not all have been fully characterized.
(Information provided by RefSeq, Feb 2011)
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