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ELK Biotechnology Ku-70 (Acetyl Lys542) rabbit pAb
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Ku-70 (Acetyl Lys542) rabbit pAb는 인간, 생쥐, 랫드 시료에 반응하는 폴리클로날 항체로, DNA 복구 관련 단백질 Ku70의 아세틸화 부위를 인식합니다. WB, IHC, IF, ELISA에 적합하며, 고순도 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.
- 판매단위
- pk
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ELK Biotechnology ES1108-100UL Ku-70 (Acetyl Lys542) rabbit pAb, 100UL pk판매 단위 pk ·
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ELK Biotechnology ES1108-50UL Ku-70 (Acetyl Lys542) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Ku-70 (Acetyl Lys542) rabbit pAb
제품명
Ku-70 (Acetyl Lys542) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC-p: 1/100–1/300; ELISA: 1/20000 (other applications not yet tested) |
| Immunogen | Synthesized acetyl-peptide derived from the human Ku-70 around the acetylation site of K542 |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 100, 70 kDa |
| Gene ID (Human) | 2547 |
| Human Swiss-Prot No. | P12956 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Rat, Mouse |
Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase and is involved in the repair of nonhomologous DNA ends such as those required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
[Provided by RefSeq, Jul 2008]
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