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ELK Biotechnology Ku-70 (Acetyl Lys539) rabbit pAb
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ELK Biotechnology Ku-70 (Acetyl Lys539) rabbit pAb

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Ku-70 (Acetyl Lys539) rabbit pAb는 인간 Ku-70 단백질의 K539 아세틸화 부위를 인식하는 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 적합하며 DNA 손상 복구 연구에 활용됩니다. 핵 및 염색체 국소화 단백질 검출에 유용합니다.

판매단위
pk
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ELK Biotechnology ES1107-100UL Ku-70 (Acetyl Lys539) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1107-50UL Ku-70 (Acetyl Lys539) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Ku-70 (Acetyl Lys539) rabbit pAb

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Ku-70 (Acetyl Lys539) rabbit pAb

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항목 내용
Product name Ku-70 (Acetyl Lys539) rabbit pAb
Alternative Names XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6
Applications WB; IHC; IF; ELISA
Recommended Dilutions WB: 1/500–1/2000
IHC-p: 1/100–1/300
ELISA: 1/20000
Not yet tested in other applications
Immunogen Synthesized acetyl-peptide derived from human Ku-70 around the acetylation site of K539
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 70 kDa
GeneID (Human) 2547
Human Swiss-Prot No P12956
Cellular Localization Nucleus, Chromosome
Species Reactivity Human; Rat; Mouse

Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa.
The complex functions as a single-stranded DNA-dependent ATP-dependent helicase and may be involved in the repair of nonhomologous DNA ends, such as those required for double-strand break repair, transposition, and V(D)J recombination.
High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
[provided by RefSeq, Jul 2008]

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