ELK Biotechnology Histone H4 (Acetyl Lys8) rabbit pAb
Histone H4 (Acetyl Lys8) rabbit polyclonal antibody로, 인간 및 설치류 등 다양한 종에 반응합니다. WB, IHC, IF, ELISA에 적합하며, 핵 및 염색체 내 히스톤 단백질 연구에 사용됩니다. 합성 펩타이드 면역원으로 제작되었습니다.
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Histone H4 (Acetyl Lys8) rabbit pAb
제품 개요
Histone H4 (Acetyl Lys8) rabbit polyclonal antibody는 인간 Histone H4의 Lys8 아세틸화 부위 주변에서 합성된 펩타이드를 면역원으로 제작된 항체입니다. 핵 및 염색체 내 히스톤 단백질 구조 연구에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H4 (Acetyl Lys8) rabbit pAb |
| Alternative Names | HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4FD; HIST1H4L; H4/K; H4FK; H4K8AC |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Histone H4 around the acetylated site of Lys8 (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 11 kDa |
| GeneID (Human) | 121504 / 554313 / 8294 / 8359 / 8360 / 8361 / 8362 / 8363 / 8364 / 8365 / 8366 / 8367 / 8368 / 8370 |
| Human Swiss-Prot No. | P62805 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat, Monkey |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction. This gene is intronless and encodes a replication-dependent histone belonging to the histone H4 family. Transcripts lack polyA tails but contain a palindromic termination element and are located in the histone microcluster on chromosome 6p21.33. (RefSeq, Aug 2015)
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