ELK Biotechnology Histone H3 (Acetyl Lys23) rabbit pAb
Histone H3 (Acetyl Lys23) rabbit polyclonal antibody로, 인간, 마우스, 랫트 시료에서 사용 가능. WB, IF, ELISA에 적합하며, 핵 및 염색체에 위치한 히스톤 H3 단백질의 아세틸화 상태를 검출. 고순도 IgG, 1 mg/ml, -20°C 보관.
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Histone H3 (Acetyl Lys23) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Acetyl Lys23) rabbit pAb |
| Alternative Names | HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3; H3k23AC |
| Applications | WB; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunofluorescence: 1/200–1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against a synthesized peptide derived from human Histone H3 around the acetylated site of Lys23 (AA range: -9–40). |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kD |
| GeneID (Human) | 8350, 8351, 8352, 8353, 8354, 8355, 8356, 8357, 8358, 8968, 126961, 333932, 653604, 3020, 3021 |
| Human Swiss-Prot No. | P68431, Q71DI3, P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through interaction of a linker histone (H1) with the DNA between nucleosomes to form higher order chromatin structures.
This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails and instead contain a palindromic termination element. The gene is found in the large histone gene cluster on chromosome 6p22–p21.3.
(Provided by RefSeq, Aug 2015)
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