ELK Biotechnology Histone H3 (Di Methyl Lys5) rabbit pAb
Histone H3 (Di Methyl Lys5) rabbit pAb는 인간 Histone H3의 K5 이중메틸화 부위를 인식하는 고특이성 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 사용 가능하며 핵 내 히스톤 단백질 검출에 적합합니다. 고순도 IgG, 1 mg/ml 농도로 제공됩니다.
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Histone H3 (Di Methyl Lys5) rabbit pAb
제품 개요
Histone H3 (Di Methyl Lys5) rabbit pAb는 인간 Histone H3 단백질의 K5 이중메틸화 부위를 인식하도록 설계된 폴리클로날 항체입니다. 세포 핵 및 염색체 내 히스톤 구조 연구에 적합하며, 다양한 면역학적 분석에 활용할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Di Methyl Lys5) rabbit pAb |
| Alternative Names | H3K5ME2; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; H3F; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3; H3F3C; Histone H3.3C; Histone H3.5 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC-p: 1/100–1/300; ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from human Histone H3 around the di-methylation site of K5 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kD |
| GeneID (Human) | 8350, 8351, 8352, 8353, 8354, 8355, 8356, 8357, 8358, 8968, 126961, 333932, 653604, 3020, 3021, 440093 |
| Human Swiss-Prot No | P68431, Q71DI3, P84243, Q6NXT2 |
| Cellular Localization | Nucleus; Chromosome |
| Species Reactivity | Human; Mouse; Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through interaction of linker histone H1 with DNA between nucleosomes to form higher-order chromatin structures. The gene encoding histone H3 is intronless and replication-dependent, located in the large histone gene cluster on chromosome 6p22-p21.3.
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