ELK Biotechnology Histone H3 (Mono Methyl Lys37) rabbit pAb
Histone H3의 Lys37 단일 메틸화 부위를 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 핵 및 염색체에 위치한 H3 단백질 연구에 활용됩니다.
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Histone H3 (Mono Methyl Lys37) rabbit pAb
제품 개요
Histone H3 (Mono Methyl Lys37) rabbit pAb는 인간 Histone H3의 K37 단일 메틸화 부위를 인식하도록 제작된 토끼 폴리클로날 항체입니다. 다양한 종에서의 히스톤 변형 연구 및 염색질 구조 분석에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Mono Methyl Lys37) rabbit pAb |
| Alternative Names | H3K37ME1; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3; H3F3C; Histone H3.3C; Histone H3.5 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC-p: 1/100–1/300; ELISA: 1/20000 (기타 응용은 미검증) |
| Immunogen | Synthesized peptide derived from human Histone H3 around the mono-methylation site of K37 |
| Host | Rabbit |
| Storage | -20°C, 1년 보관 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kDa |
| Gene ID (Human) | 8350, 8351, 8352, 8353, 8354, 8355, 8356, 8357, 8358, 8968, 126961, 333932, 653604, 3020, 3021, 440093 |
| Human Swiss-Prot No. | P68431, Q71DI3, P84243, Q6NXT2 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Approximately 146 bp of DNA wraps around a nucleosome, an octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). Chromatin fibers are further compacted through interactions with linker histone H1 to form higher-order structures. This gene is intronless and encodes a replication-dependent histone H3 family member. Transcripts lack polyA tails and contain a palindromic termination element. The gene is located within the large histone gene cluster on chromosome 6p22-p21.3 (RefSeq, Aug 2015).
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