ELK Biotechnology Cleaved-Caspase-7 p20 (D198) rabbit pAb
Cleaved-Caspase-7 p20 (D198) rabbit polyclonal antibody로, 인간 Caspase-7 유래 펩타이드에 대해 제작되었습니다. WB와 ELISA에 적합하며 세포자멸사 연구에 활용됩니다. IgG 아이소타입, 1 mg/ml 농도, -20°C에서 1년 보관 가능합니다.
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Cleaved-Caspase-7 p20 (D198) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cleaved-Caspase-7 p20 (D198) rabbit pAb |
| Alternative Names | CASP7; MCH3; Caspase-7; CASP-7; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 7 (AA range: 149–198) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 20 kD |
| GeneID (Human) | 840 |
| Human Swiss-Prot No | P55210 |
| Cellular localization | Cytoplasm |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, activated upon cell death stimuli, and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
[provided by RefSeq, May 2012]
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