ELK Biotechnology Cleaved-Caspase-2 p18 (G170) rabbit pAb
Cleaved-Caspase-2 p18 (G170) rabbit pAb는 인간, 마우스, 랫에서 반응하는 폴리클로날 항체로, apoptosis 관련 단백질 Caspase-2를 검출합니다. WB 및 ELISA에 적합하며, 고특이성과 재현성을 제공합니다. 장기 보관 시 -20°C에서 안정적입니다.
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Cleaved-Caspase-2 p18 (G170) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cleaved-Caspase-2 p18 (G170) rabbit pAb |
| Alternative Names | CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 2 p18 N-terminal (AA range: 151-200) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 18 or 35 kD |
| Gene ID (Human) | 835 |
| Human Swiss-Prot No | P42575 |
| Cellular Localization | Nucleus, cytoplasm, mitochondrion, cytosol, membrane |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and tumorigenesis suppression. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer’s disease, Huntington’s disease, and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
[Provided by RefSeq, Jan 2011]
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