ELK Biotechnology Cleaved-Caspase-3 p17 (D175) rabbit pAb
Cleaved-Caspase-3 p17 (D175) rabbit polyclonal antibody로 세포 사멸(apoptosis) 연구에 적합. WB, IF, IHC, ELISA 등 다양한 응용 가능. 인간, 마우스, 랫트 시료에 반응하며 고순도 IgG 형식으로 제공. 장기 보관 시 -20°C에서 안정적 유지.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology Cleaved-Caspase-3 p17 (D175) rabbit pAb
Cleaved-Caspase-3 p17 (D175) rabbit pAb
제품 개요
Cleaved-Caspase-3 p17 (D175) rabbit polyclonal antibody는 세포 사멸 과정에서 활성화된 Caspase-3 단편(p17)을 검출하기 위한 항체입니다. 인간, 마우스, 랫트 시료에서 높은 특이성과 재현성을 보입니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cleaved-Caspase-3 p17 (D175) rabbit pAb |
| Alternative Names | CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1 |
| Applications | WB; IF; IHC; ELISA |
| Recommended Dilutions | WB 1:500–2000, IHC-p 1:50–300, IF 1:50–300 |
| Immunogen | Synthesized peptide derived from human Caspase 3 (AA range: 126–175) |
| Host Species | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17, 34 kD |
| GeneID (Human) | 836 |
| Human Swiss-Prot No | P42574 |
| Cellular Localization | Cytoplasm |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family, which plays a key role in the execution phase of apoptosis. Caspases are synthesized as inactive proenzymes that are activated through proteolytic cleavage at conserved aspartic residues. Activated Caspase-3 cleaves and activates caspases 6, 7, and 9, and is itself processed by caspases 8, 9, and 10. It is the predominant caspase involved in amyloid-beta precursor protein cleavage, associated with neuronal death in Alzheimer’s disease. Alternative splicing produces two transcript variants encoding the same protein. (RefSeq, Jul 2008)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.