ELK Biotechnology Lamin B1 Rabbit pAb
Rabbit polyclonal antibody against Lamin B1 for WB and IHC applications. Reacts with human, rat, and mouse samples. Provides high specificity for nuclear lamina protein detection. Stable storage in PBS/glycerol solution at -20°C.
- 카탈로그번호
- EA041-xxxxx (2개 옵션)
- 판매단위
- pk
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Lamin B1 Rabbit pAb
제품 개요
Lamin B1 Rabbit pAb는 핵막 인접 단백질 매트릭스 구성 요소인 Lamin B1을 인식하는 토끼 유래 폴리클로날 항체입니다. 핵 안정성, 염색질 구조, 유전자 발현 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Lamin B1 Rabbit pAb |
| Reactivity | Human, Rat, Mouse |
| Alternative Names | ADLD, LMB1, LMNB1, MGC111419, OTTHUMP00000159218 |
| Source | Rabbit |
| Applications | WB, IHC |
| Recommended dilutions | WB: 1:1,000–3,000 / IHC: 1:500–1,000 |
| Immunogen | Recombinant Protein |
| Storage | PBS with 0.02% sodium azide and 50% glycerol, pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed band | 68, 45 kDa |
| GeneID (Human) | 4001 |
| Human Swiss-Prot No | P20700 |
| Cellular localization | Mitochondrion inner membrane |
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure, and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
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