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ELK Biotechnology IκB α Rabbit pAb
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Rabbit polyclonal antibody against IκBα for WB and IHC applications. Reacts with human and rat samples. Targets NF-κB inhibitor protein involved in inflammatory signaling. Supplied in PBS with glycerol for stable storage at -20°C.
- 판매단위
- pk
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ELK Biotechnology EA213-100UL IκB α Rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology EA213-50UL IκB α Rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology IκB α Rabbit pAb
ELK Biotechnology IκB α Rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | IκB α Rabbit pAb |
| Reactivity | Human, Rat |
| Alternative Names | I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody |
| Source | Rabbit |
| Applications | WB, IHC |
| Species | Human |
| Recommended dilutions | WB 1:2,000–5,000 / IHC 1:200–500 |
| Immunogen | Recombinant Protein |
| Storage | PBS with 0.02% sodium azide and 50% glycerol (pH 7.4). Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed band | 40 kDa |
| GeneID (Human) | 4792 |
| Human Swiss-Prot No | P25963 |
| Cellular localization | Cytoplasm, Nucleus |
Background
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.
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