
ELK Biotechnology α-actinin Rabbit pAb
Rabbit polyclonal antibody targeting α-actinin for use in WB and IHC. Reacts with rat and mouse samples. Provides strong specificity to actin cytoskeletal structures. Stored in PBS with glycerol at -20°C to maintain stability.
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ELK Biotechnology α-actinin Rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | α-actinin Rabbit pAb |
| Reactivity | Rat, Mouse |
| Alternative Names | actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody |
| Source | Rabbit |
| Applications | WB, IHC |
| Species | Human |
| Recommended dilutions | WB 1:1,000–2,000 / IHC 1:200–500 |
| Immunogen | Recombinant Protein |
| Storage | PBS with 0.02% sodium azide and 50% glycerol, pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed band | 103 kDa |
| GeneID (Human) | 87 |
| Human Swiss-Prot No | P12814 |
| Cellular localization | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane |
Background
α-Actinin belongs to the spectrin family of cytoskeletal proteins. It is essential for the attachment of actin filaments to the Z-lines in skeletal muscle cells and to the dense bodies in smooth muscle cells. The functional protein forms an anti-parallel dimer that cross-links thin filaments in adjacent sarcomeres, enabling coordinated contractions between sarcomeres along the horizontal axis.
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