Thermo Fisher Scientific TP53INP2 Polyclonal Antibody
TP53INP2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, IHC 및 ICC/IF에 적합합니다. Rabbit IgG 기반으로 제조되었으며, 액상 형태로 1 mg/mL 농도 유지. -20°C 보관, 연구용 전용 시약입니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
- Publications: [참고문헌 링크]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: [참고문헌 링크]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human TP53INP2 (CVRRLQRARQRAERH) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555323 |
Target Information
TP53INP2 (tumor protein p53 inducible nuclear protein 2), also known as DOR or PINH, is a 220 amino acid nuclear protein expressed in developing murine brain and spinal cord, as well as in sensory and motor neuron tracts of the peripheral nervous system.
This novel protein is involved in the autophagy of mammalian cells and translocates from the nucleus to autophagosome structures after activation of autophagy by rapamycin or starvation.
TP53INP2 is necessary for autophagosome development and acts as a scaffold protein recruiting LC3 and LC3-related proteins (e.g., GABARAP, GABARAP-like2) to the autophagosome membrane via interaction with TMEM49.
The TP53INP2 gene is located on human chromosome 20, which contains approximately 63 million bases encoding over 600 genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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