Thermo Fisher Scientific TP53INP2 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:100
• Publications: [참고문헌 링크]

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500
• Publications: [참고문헌 링크]

Product Specifications

Target Information

TP53INP2 (tumor protein p53 inducible nuclear protein 2), also known as DOR or PINH, is a 220 amino acid nuclear protein expressed in developing murine brain and spinal cord, as well as in sensory and motor neuron tracts of the peripheral nervous system.
This novel protein is involved in the autophagy of mammalian cells and translocates from the nucleus to autophagosome structures after activation of autophagy by rapamycin or starvation.
TP53INP2 is necessary for autophagosome development and acts as a scaffold protein recruiting LC3 and LC3-related proteins (e.g., GABARAP, GABARAP-like2) to the autophagosome membrane via interaction with TMEM49.
The TP53INP2 gene is located on human chromosome 20, which contains approximately 63 million bases encoding over 600 genes.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.