
Thermo Fisher Scientific Flt3/CD135 Monoclonal Antibody (FLT3/2458)
인간 FLT3/CD135 단백질을 인식하는 마우스 단클론 항체입니다. 면역조직화학(IHC) 실험에 적합하며, 단백질 A/G로 정제된 액상 형태입니다. PBS 완충액에 0.05% BSA 및 sodium azide가 포함되어 있으며, 4°C에서 보관합니다.
- 카탈로그번호
- 2322-MSM1-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Flt3/CD135 Monoclonal Antibody (FLT3/2458)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FLT3/2458 |
| Immunogen | Recombinant full-length human FLT3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FLT3 is a tyrosine protein kinase that belongs to the growth factor receptor tyrosine kinase family. Activation occurs upon binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, inducing receptor homodimerization and autophosphorylation. The activated receptor phosphorylates downstream effectors involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Constitutive activation due to mutations can lead to acute myeloid leukemia and acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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