Thermo Fisher Scientific MED12L Polyclonal Antibody
인간 MED12L 단백질에 특이적인 토끼 폴리클로날 항체로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 글리세롤을 포함한 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA557827
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MED12L. Recombinant protein control fragment (Product #RP-96365) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643844 |
Product Specific Information
Immunogen sequence:
LSVTASTRPR SPVGENADEH YSKDHDVKME IFSPMPGESC ENANTSLGRR MSVNCEKLVK REKPRELIFP SNYDLL
Ortholog sequence identity:
- Mouse: 86%
- Rat: 84%
Target Information
MED12L, also known as KIAA1635, TNRC11L, TRALP, and TRALPUSH, belongs to the Mediator complex subunit 12 family.
MED12L may be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.
MED12L functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
It is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and general transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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