Thermo Fisher Scientific MRPL28 Polyclonal Antibody
Human MRPL28 단백질에 특이적인 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS와 글리세롤 버퍼에 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPL28. Recombinant protein control fragment (Product #RP-95498). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644137 |
Product Specific Information
Immunogen sequence:
RRAAIYDKYK EFAIPEEEAE WVGLTLEEAI EKQRLLEEKD PVPLFKIYVA ELIQQLQQQA LSEPAVVQKR ASGQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 80%
- Rat: 81%
Target Information
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein belonging to the ribosomal protein L28P family.
MRP-L28 may serve as a therapeutic reagent for HLA-A24 (A24) patients, as this antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290 targeting the A24 serotype.
HLA-A24 (A24) is an HLA-A serotype common in Austronesia and several indigenous populations.
MRP-L28 is expressed in various normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung, and retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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