Thermo Fisher Scientific INHA Monoclonal Antibody (OTI12F11), TrueMAB
인간 INHA 단백질(아미노산 62-232)을 표적하는 Mouse IgG1 단클론 항체. Western blot에 1:2,000 희석으로 검증됨. 액상 형태로 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 저장. 종양 억제 및 생식 관련 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 62–232 of human INHA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum inhibin levels correlate with granulosa-cell tumor size and can serve as a marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit gene expression is suppressed and not detectable in poorly differentiated tumor cells. Expression varies among gonadal and extragonadal tissues, suggesting inhibin functions as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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