Thermo Fisher Scientific IL21R Polyclonal Antibody
Human IL21R 단백질을 인식하는 Rabbit Polyclonal Antibody. Western Blot에서 0.5–2 µg/mL로 사용 가능. Protein G로 정제된 액상 항체로 PBS + 0.2% gelatin buffer에 보관. IL21 신호전달 연구 및 면역세포 활성 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
- Suggested positive control: Raji whole cell lysate, NIH-3T3 whole cell lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides corresponding to residues 65–80 and 505–521 of human IL-21R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.2% gelatin |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2280184 |
Product Specific Information
- This antibody is predicted to react with mouse samples based on sequence homology.
- Suggested positive control: Raji whole cell lysate, NIH-3T3 whole cell lysate.
Target Information
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors and forms a heterodimeric receptor complex with the common gamma-chain, which is shared by IL2 and IL5 receptors. This receptor mediates IL21 growth signals and plays an essential role in the proliferation and differentiation of T cells, B cells, and NK cells. Ligand binding activates downstream signaling molecules such as JAK1, JAK3, STAT1, and STAT3. Mouse knockout studies suggest involvement in immunoglobulin regulation. Three alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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