Thermo Fisher Scientific KLF4 Monoclonal Antibody (6C5)
KLF4 단백질을 표적하는 Rabbit IgG 단일클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간 KLF4(aa 1–500)를 면역원으로 사용하며, 액상 형태로 1 mg/mL 농도입니다. -20°C 보관, 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific KLF4 Monoclonal Antibody (6C5)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C5 |
| Immunogen | Human KLF4 (amino acids 1–500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Kruppel-like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to the conserved Kruppel-like factor family of DNA-binding zinc finger transcription factors.
KLF4 plays a key role in cellular processes such as endothelial signaling, adipogenesis, differentiation, embryogenesis, and cell cycle control. As one of the four Yamanaka factors, it is essential for reprogramming differentiated cells into pluripotent stem cells.
Nuclear localization is associated with oncogenic function, while cytosolic localization relates to tumor-suppressive effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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