Thermo Fisher Scientific NCOA6 Polyclonal Antibody
Human NCOA6 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 핵 수용체 공동활성화 연구에 활용 가능하며, 장기 보관 시 -20°C에서 안정적입니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NCOA6. Recombinant protein control fragment (Product #RP-106262) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663309 |
Product Specific Information
Immunogen sequence:
TSVRSIVTTLV PSELISAVPT TKSNHGGIAS ESLAGGLVEE KVGSHPELLP SIAPSQNLVS KETSTTALQA SVARPELEVN AAIVSGQSSE PKEIVEKSKI PGRRNSRTEE PTVASESVEN GHRKRSSRP
- Highest antigen sequence identity to the following orthologs: mouse 85%, rat 85%.
Target Information
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR), and prostanoids (PPARs).
Functions as a general coactivator and may also participate in NF-kappa-B pathway activation.
Potentially coactivates expression through chromatin remodeling and interaction with histone acetyltransferase proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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