
Thermo Fisher Scientific OTC Monoclonal Antibody (OTI4G8), TrueMAB
OTC 단백질을 인식하는 Mouse monoclonal antibody로 Western Blot 및 IHC(P) 검증 완료. Human 시료 반응성. Affinity chromatography로 정제된 1 mg/mL 액상 시약. -20°C 보관, 반복 동결·해동 피할 것.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–354 of human OTC produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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