Thermo Fisher Scientific NMBR Monoclonal Antibody (466505)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

0.25 µg per million cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

466505

Immunogen

NS0 mouse myeloma cell line transfected with human NMBR Met1-Met390 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NMBR,uniProtId:P28336-1,ncbiNodeId:9606,antigenRange:1-390,antigenLength:390,antigenImageFileName:MA5-24187_NMBR_P28336-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24187_NMBR_P28336-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2609065

Product Specific Information

This antibody stains human Neuromedin B R/NMBR transfectants but not irrelevant transfectants.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.