Thermo Fisher Scientific NMBR Monoclonal Antibody (466505)
인간 NMBR(Neuromedin B receptor)을 특이적으로 인식하는 마우스 단클론 항체. Flow Cytometry에 최적화되어 있으며, 동결건조 형태로 제공. Protein A/G로 정제되었고 PBS+trehalose 버퍼에 재구성 가능. 연구용으로만 사용.
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Applications
- Flow Cytometry (Flow): 0.25 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 466505 |
| Immunogen | NS0 mouse myeloma cell line transfected with human NMBR Met1–Met390 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609065 |
Product Specific Information
This antibody stains human Neuromedin B R/NMBR transfectants but not irrelevant transfectants.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
NMBR (Neuromedin B receptor) is a Bombesin receptor that activates phospholipase and protein kinase C, enhancing calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and gastrointestinal epithelial tissues.
Expression has been reported in brain (olfactory bulb, thalamus), colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. It is also present in cancers of lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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