Thermo Fisher Scientific PCDH18 Polyclonal Antibody
Thermo Fisher Scientific의 PCDH18 Polyclonal Antibody는 인간 PCDH18 단백질을 인식하는 rabbit IgG 항체로, Western blot에 최적화되어 있습니다. 액상 형태로 제공되며, 높은 순도의 Affinity Chromatography 정제 제품입니다. 뇌 발달 관련 연구에 적합합니다.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human PCDH18 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577178 |
Product Specific Information
- Peptide sequence: MHQMNAKMHF RFVFALLIVS FNHDVLGKNL KYRIYEEQRV GSVIARLSED
- Sequence homology:
Cow: 100%
Dog: 93%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 79%
Rat: 100%
Target Information
Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules.
Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs.
Tissue screening revealed broad expression in brain, liver, heart, kidney, lung, and trachea.
PCDH18 expression is temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development.
It is also expressed in the developing zebrafish neural tube and central nervous system, suggesting a role in brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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