Thermo Fisher Scientific GNPDA2 Polyclonal Antibody
GNPDA2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(Paraffin) 분석에 적합합니다. 인간, 생쥐, 랫트 시료에서 반응하며, 고순도의 친화 크로마토그래피 정제 항체입니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GNPDA2 (Accession Q8TDQ7), corresponding to amino acid residues P29–R79 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850055 |
Product Specific Information
Antibody detects endogenous levels of total GNPDA2.
Target Information
GNPDA2 (Glucosamine-6-phosphate deaminase) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium.
GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered and is structurally and functionally closer to the E. coli enzyme than GNPDA1.
GNPDA1 exhibits greater affinity for ammonium than either GNPDA2 or the E. coli enzyme, suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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