Thermo Fisher Scientific CRHR1 (extracellular) Polyclonal Antibody
CRHR1 단백질의 extracellular 영역을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot 및 IHC(Frozen)에 사용 가능. Lyophilized 형태로 제공되며, -20°C 보관. 스트레스 반응 및 불안 관련 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:1,000 | - |
| Immunohistochemistry (IHC) | - | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:600 | - |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide ENLSLTSNVSGLQC, corresponding to amino acid residues 31–44 of rat CRHR1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.85 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735685 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating stress response and anxiety-related behaviors.
Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease.
Multiple isoforms of CRFR1 are produced by alternative splicing.
CRFR1 is expressed in pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin.
ESTs have been isolated from human brain, eye, colon, and embryo libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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