Thermo Fisher Scientific ZC3HAV1 Polyclonal Antibody
ZC3HAV1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. 인간, 생쥐, 랫트에 반응하며 Western blot과 IHC(P)에서 사용 가능합니다. 액상 형태로 1 mg/mL 농도이며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ZC3HAV1 (Accession Q7Z2W4), corresponding to amino acid residues A288–D338 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854063 |
Product Specific Information
Antibody detects endogenous levels of total ZC3HAV1.
Target Information
The zinc finger antiviral protein (ZC3HAV1) is a CCCH-type zinc finger protein that induces innate immunity against retroviral infections by preventing accumulation of viral RNAs in the cytoplasm. It recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state but shuttles between nucleus and cytoplasm in an XPO1-dependent manner. ZAP is a direct target gene of IRF3 in antiviral responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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