
Thermo Fisher Scientific PYDC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PYDC1 (ASC2). Validated for Western blot at 1:1,000 dilution. Predicted cross-reactivity with mouse and rat. Supplied as liquid, 1 mg/mL, unconjugated. Store at -20°C, shipped on wet ice.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human ASC2 (PYDC1, UniProt ID: Q8WXC3-1, range 1–28, length 89 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691780 |
Product Specific Information
- Predicted to react with Mouse and Rat samples.
Target Information
ASC2 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation.
It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes, and inhibits NF-kappa-B activation by cytokines and LPS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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