Thermo Fisher Scientific RANBP1 Polyclonal Antibody
RANBP1 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(P) 실험에 적합하며, Human, Mouse, Rat에 반응. 항원 친화 크로마토그래피로 정제, 1 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5141086
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within N-terminal human RanBP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2932538 |
Target Information
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kDa protein that binds to RAN complexed with GTP but not GDP. It does not activate GTPase activity of RAN but markedly increases GTP hydrolysis by RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that shares 92% similarity with its mouse homolog. In both mammalian cells and yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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