Thermo Fisher Scientific GPLD1 Polyclonal Antibody
Thermo Fisher Scientific GPLD1 Polyclonal Antibody는 인간 및 마우스 GPLD1 단백질을 검출하는 고품질 항체입니다. Western blot, IHC, ICC/IF에 적합하며, 고순도 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GPLD1 (Accession P80108), corresponding to amino acid residues F247–S297 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853344 |
Product Specific Information
Antibody detects endogenous levels of total GPLD1.
Target Information
GPLD1 is expressed in numerous tissues and cells and specifically cleaves GPI-anchored proteins. The liver exhibits the highest level of GPI-PLD expression and is the primary source of GPLD1 in serum. GPLD1 associates with apolipoproteins AI and AIV in serum. Elevated serum GPLD1 levels are linked to insulin resistance and increased serum triglycerides. Many surface proteins are attached to eukaryotic cell membranes via glycosylphosphatidylinositol (GPI) anchors, and cleavage of the GPI moiety by GPLD1—the only known enzyme that cleaves GPI anchors—may regulate protein attachment to the cell surface or their release into the extracellular environment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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