Thermo Fisher Scientific PIH1D1 Polyclonal Antibody
PIH1D1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 종에 반응하며, 장기 보관 시 -20°C에서 안정적으로 유지됨.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PIH1D1. Recombinant protein control fragment (Product #RP-98914). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645561 |
Product Specific Information
Immunogen sequence:
MANPKLLGLE LSEAEAIGAD SARFEELLLQ ASKELQQAQT TRPESTQIQP QPGFCIKTNS SEGKVFINIC HSPSIPPPAD VTEEELLQML EEDQAGFRIP MS
Highest antigen sequence identity to orthologs:
- Mouse: 79%
- Rat: 83%
Target Information
PIH1D1 is involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026).
It recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451).
Mediates interaction of TELO2 with the R2TP complex, necessary for the stability of MTOR and SMG1 (PubMed:20864032).
Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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