Thermo Fisher Scientific Claudin 19 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Target Information

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.
Defects in this gene cause hypomagnesemia renal with ocular involvement (HOMGO), a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria, and nephrocalcinosis, associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia, and nystagmus.
Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
[Provided by RefSeq, Jun 2010]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.