Thermo Fisher Scientific MUS81 Polyclonal Antibody
Human MUS81 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 고순도 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로 DNA 구조 특이적 엔도뉴클레이스 복합체 연구에 적합.
- 카탈로그번호
- PA563743
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MUS81 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MUS81. Recombinant protein control fragment (Product # RP-89866) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644314 |
Product Specific Information
Immunogen sequence:
LVEEHGSVHN LSLPESTLLQ AVTNTQVIDG FFVKRTADIK ESAAYLALLT RGLQRLYQGH TLRSRPWGTP GNPESGAMTS PNPLCSLLTF SDFNAGAIKN KAQSVREVFA RQLMQVRGVS GEKAAALVDR YSTPA
Sequence identity:
- Mouse: 89%
- Rat: 89%
Target Information
MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5′-end at the branch nick. Typical substrates include 3′-flap structures, replication forks, and nicked Holliday junctions.
May be required in mitosis for the processing of stalled or collapsed replication forks.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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