Thermo Fisher Scientific MUS81 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MUS81. Recombinant protein control fragment (Product # RP-89866). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MUS81,uniProtId:Q96NY9-1,ncbiNodeId:9606,antigenRange:367-501,antigenLength:551,antigenImageFileName:PA5-63743_MUS81_Q96NY9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63743_MUS81_Q96NY9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644314

Product Specific Information

Immunogen sequence: LVEEHGSVHN LSLPESTLLQ AVTNTQVIDG FFVKRTADIK ESAAYLALLT RGLQRLYQGH TLRSRPWGTP GNPESGAMTS PNPLCSLLTF SDFNAGAIKN KAQSVREVFA RQLMQVRGVS GEKAAALVDR YSTPA

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.

Target Information

Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5-end at the branch nick. Typical substrates include 3-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.