Thermo Fisher Scientific ZC3HAV1 Polyclonal Antibody
인간 ZC3HAV1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 면역세포화학(ICC/IF)에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. PBS 완충액과 글리세롤로 안정화되어 장기 보관에 적합.
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Thermo Fisher Scientific ZC3HAV1 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZC3HAV1 (Product #RP-106915) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856889 |
Product Specific Information
Immunogen sequence:
RFVVLETGGE AGITRSVVAT TRARVCRRKY CQRPCDNLHL CKLNLLGRCN YSQSERNLCK YSHEVLSEEN FKVLKNHELS GLNK
Target Information
The zinc finger antiviral protein (ZC3HAV1) is a CCCH-type zinc finger protein that induces innate immunity to retroviral infections by preventing accumulation of viral RNAs in the cytoplasm. It recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication.
ZC3HAV1 is localized in the cytoplasm at steady state but shuttles between nucleus and cytoplasm in an XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in antiviral responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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