Thermo Fisher Scientific UNC5B Polyclonal Antibody
UNC5B 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 생쥐 시료에 반응합니다. IHC 및 파라핀 절편 실험에 적합하며, 액상 형태로 제공됩니다. 0.5 mg/mL 농도, PBS 버퍼와 40% 글리세롤 포함, -20°C 보관.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- View 2 publications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:100
- View publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human UNC5B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2688464 |
Product Specific Information
Predicted to react with Mouse samples.
Target Information
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308, thereby increasing its catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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