Thermo Fisher Scientific IL12RB2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1301)
IL12RB2 단백질을 표적으로 하는 알파카 유래 재조합 단일클론 항체. Flow Cytometry, ELISA, SPR 등 다양한 어세이에 사용 가능. CHO 세포에서 발현되며 1 mg/mL 농도의 액상 형태로 제공. 금속 킬레이트 크로마토그래피로 정제되어 높은 순도 보장.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Surface Plasmon Resonance (SPR)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1301 |
| Immunogen | Recombinant Human IL12RB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. Coexpression of IL12RB2 and IL12RB1 leads to formation of high-affinity IL12 binding sites and reconstitution of IL12-dependent signaling. Expression is up-regulated by interferon gamma in Th1 cells and plays a role in Th1 cell differentiation. Up-regulation is associated with infectious diseases such as Crohn’s disease and leprosy, contributing to inflammatory response and host defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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