Thermo Fisher Scientific Actin, Muscle Specific (Muscle Cell Marker) Monoclonal Antibody (SPM160)
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Thermo Fisher Scientific Actin, Muscle Specific (Muscle Cell Marker) Monoclonal Antibody (SPM160)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM160 |
| Immunogen | SDS extract of human myocardium |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved and play a crucial role in cell motility, structure, and integrity. Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actins: Major constituent of the contractile apparatus
- Beta and gamma actins: Involved in the regulation of cell motility
This antibody targets alpha actin found in skeletal muscle. Mutations in this gene are associated with:
- Nemaline myopathy type 3
- Congenital myopathy with excess thin myofilaments
- Congenital myopathy with cores
- Congenital myopathy with fiber-type disproportion
These conditions lead to muscle fiber defects.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일명: MSM1X-445-P0_Actin_Muscle_P62736-1_House_mouse.svg, MSM1X-445-P0_Actin_Muscle_P63261-1_House_mouse.svg, MSM1X-445-P0_Actin_Muscle_P63267-1_House_mouse.svg, MSM1X-445-P0_Actin_Muscle_P68032-1_House_mouse.svg, MSM1X-445-P0_Actin_Muscle_P68133-1_House_mouse.svg)
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