Thermo Fisher Scientific RPAIN Polyclonal Antibody
RPAIN 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RPAIN. Recombinant protein control fragment (Product # RP-93237) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646708 |
Product Specific Information
Immunogen sequence:
MAESLRSPRR SLYKLVGSPP WKEAFRQRCL ERMRNSRDRL LNRYRQAGSS GPGNSQNSFL VQEVMEEEWN
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 71%
- Rat: 73%
Target Information
Replication protein A (RPA) is a single-stranded DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair, and recombination.
RPA interacting protein (RPA IP) functions as an adapter protein involved in RPA nuclear import instead of the typical importin proteins.
Multiple isoforms of RPA IP exist:
- The longest isoform is localized in the cytoplasm.
- Isoform 2 is sumoylated and located in the PML nuclear body within the nucleus, mediating localization of the RPA complex and participating in DNA metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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