Thermo Fisher Scientific DELE Polyclonal Antibody
Rabbit polyclonal antibody recognizing human DELE protein. Suitable for apoptosis-related research. Supplied as a liquid at 0.3 mg/mL concentration. Store at 4°C short term or -20°C long term. For research use only.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DELE (UniProt ID: Q14154-1, antigen range: 123–213, antigen length: 515) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640508 |
Product Specific Information
Immunogen sequence:
PLDRFFSSPL WHPCSSLRQH ILPSPDGPAP RHTGLREPRL GQEEASAQPR NFSHNSLRGA RPQDPSEEGP GDFGFLHASS SIESEAKPAQ P
Highest antigen sequence identity:
- Mouse: 55%
- Rat: 59%
Target Information
DELE is a recently identified DAP3-binding protein important in the induction of death receptor-mediated apoptosis.
Cells expressing DELE are susceptible to apoptosis induced by TNF-Alpha and TRAIL, while DELE knockdown by siRNA rescues cells from apoptosis.
Reduction of DELE expression inhibits activation of caspase-3, caspase-8, and caspase-9 following stimulation by TNF-Alpha, anti-Fas, or TRAIL, indicating DELE’s role in death receptor-mediated apoptosis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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