Thermo Fisher Scientific CCDC88C Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 1475-1557. Recombinant protein control fragment (Product # if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCDC88C,uniProtId:Q9P219-1,ncbiNodeId:9606,antigenRange:1475-1557,antigenLength:2028,antigenImageFileName:PA5-144920_CCDC88C_Q9P219-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144920_CCDC88C_Q9P219-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3092328

Product Specific Information

Immunogen sequence: NGSVGKGPGD LKPKRGSPHR GSLDRTDAST DLAMRSWPSE LGSRTCSTSA TTTAPSNSTP IARHPGRTKG YNSDDNLCEP SLE

Antigen sequence identity: Mouse 78%; Rat 76%

Target Information

This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the disheveled protein and is a negative regulator of the Wnt signaling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the disheveled protein. Disheveled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.