Thermo Fisher Scientific BTNL2 Polyclonal Antibody
BTNL2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC, ELISA에 사용 가능하며, 고순도의 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 | |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Butyrophilin-like protein 2 (BTNL2) protein (246–455AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.47 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2868184 |
Target Information
BTNL2 (Butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation.
It is expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas, and leukocytes.
BTNL2 exists as at least six alternatively spliced isoforms encoded by a gene located on human chromosome 6.
Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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