Thermo Fisher Scientific MAGE1 Polyclonal Antibody
MAGE1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 생쥐, 랫트 반응성. 암 관련 항원 연구 및 면역학 연구용 시약. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human MAGEA1 (Accession P43355), amino acid residues E273–V309 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853817 |
Product Specific Information
Antibody detects endogenous levels of total MAGE1.
Target Information
Human malignant neoplasms carry rejection antigens recognized by autologous, tumor-directed, CD8+ cytolytic T lymphocyte clones (CTL). The MAGE family of genes encodes an important group of these antigens. MAGE-1 is expressed in a significant proportion of human tumors (melanoma, brain tumors, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) but not in normal tissues. Thus, MAGE-1 may serve as a marker for early cancer detection and a potential target for immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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