Thermo Fisher Scientific GAMT Monoclonal Antibody (3H4)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1 ng/mL

-

Product Specifications

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

3H4

Immunogen

GAMT (NP_000147.1, 138 a.a. approximately 235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GAMT,uniProtId:Q14353-1,ncbiNodeId:9606,antigenRange:138-235,antigenLength:236,antigenImageFileName:H00002593-M04_GAMT_Q14353-1_House_mouse.svg,antigenImageFileNamePDP:H00002593-M04_GAMT_Q14353-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: PLSEETWHTH QFNFIKNHAF RLLKPGGVLT YCNLTSWGEL MKSKYSDITI MFEETQVPAL LEAGFRRENI RTEVMALVPP ADCRYYAFPQ MITPLVTK

Target Information

GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.