Thermo Fisher Scientific PTPRB Polyclonal Antibody
Human PTPRB 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 최적화됨. 고순도 affinity chromatography 정제, 1 mg/mL 농도, PBS/glycerol buffer에 보존. 세포 성장 및 분화 관련 신호전달 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PTPRB (UniProt ID: P23467-1, antigen range: 316–335) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691600 |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This receptor-type PTP contains:
- An extracellular domain with multiple fibronectin type III repeats
- A single transmembrane segment
- One intracytoplasmic catalytic domain
It interacts with neuronal receptors and adhesion molecules (e.g., contactin, tenascin C), and sodium channels, suggesting roles in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-68309_PTPRB_P23467-1_Rabbit.svg 및 PA5-68309_PTPRB_P23467-1_Rabbit_PDP.jpeg)
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