Thermo Fisher Scientific RTF1 Polyclonal Antibody
RTF1 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 및 마우스에 반응합니다. Western blot과 ELISA에 적합하며, 고순도의 Affinity Chromatography로 정제되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 300–400 of human RTF1 (NP_055953.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.57 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855744 |
Product Specific Information
Immunogen sequence:
LAKKQPLKTS EVYSDDEEEE EDDKSSEKSD RSSRTSSSDE EEEKEEIPPK SQPVSLPEEL NRVRLSRHKL ERWCHMPFFA KTVTGCFVRI GIGNHNSKPV Y
Target Information
Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, exhibit high sequence homology with the S. cerevisiae kinase Ste20 involved in pheromone signaling.
These isoforms complex with Rac1 and Cdc42 in their active GTP-bound state, inhibiting GTPase activity and leading to autophosphorylation.
Phosphorylation of Ser141 and Thr402 correlates with gammaPAK activation. Once phosphorylated, the PAK isoforms disassociate to interact with downstream substrates.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-110333_RTF1_Q92541-1_Rabbit.svg
- PA5-110333_RTF1_Q92541-1_Rabbit_PDP.jpeg
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