Thermo Fisher Scientific NTE Polyclonal Antibody
Human NTE 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20~1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% 글리세롤 버퍼에 보관. 신경세포 분화 연구 및 NTE 관련 신경퇴행성 질환 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NTE. Recombinant protein control fragment (Product #RP-89959) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644842 |
Product Specific Information
Immunogen sequence:
DVGYQYGKAV FGGWSRGNVI EKMLTDRRST DLNESRRADV LAFPSSGFTD LAEIVSRIEP PTSYVSDGCA DGEESDCLTE YEEDAGPDCS RDEGGSPEGA SPSTASEMEE EKSILRQRR
Antigen sequence identity:
- Mouse: 96%
- Rat: 96%
Target Information
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It functions in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is a target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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