Thermo Fisher Scientific Phospho-ARHGAP42 (Tyr792) Polyclonal Antibody
ARHGAP42 단백질의 인산화 Tyr792 부위를 특이적으로 인식하는 폴리클로날 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 인간, 마우스, 랫트 시료에 반응합니다. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARHGAP42 (Accession A6NI28), corresponding to amino acid residues around phosphorylated Tyr792. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816798 |
Product Specific Information
This antibody detects endogenous levels of ARHGAP42 only when phosphorylated at Tyr792.
Target Information
The ARHGAP42 gene encodes a Rho GTPase-activating protein (RhoGAP) and member of the GRAF or BAR-PH family of proteins. Expression is enriched in vascular smooth muscle cells, where the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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